当前位置:
首页
>
电子教材
>
详细信息
快速检索
数据库:
各中心已购纸本教材
各中心已购电子教材
国内高校课程
国外著名大学课程
外文原版教材出版信息
外文影印版教材出版信息
名校购书信息
关键词:
Chemical Engineering in the Pharmaceutical Industry: Drug Product Design, Development, and Modeling, 2Nd Edition
书目信息
ISBN:
9781119285496
本馆索书号:
中图分类号:
TQ
中文译名:
作者:
Mary T. am Ende
编者:
语种:
英语
出版信息
出版社:
Wiley
出版地:
出版年:
2019
版本:
版本类型:
原版
丛书题名:
卷期:
文献信息
关键词:
前言:
摘要:
The 1st edition of Chemical Engineering in the Pharmaceutical Industry contained 44 Chapters and was 887 pages on 8 x 11 page format. The book was divided into 3 Parts: API (Active pharmaceutical ingredients), Drug Products, and Analytics. The new edition is significantly expanded and is split into two volumes, across the broad topics of Drug Substance and Drug Product, totaling 76 Chapters. Most of the original chapters are updated or expanded with additional example calculations of interest to Chemical Engineers. The API volume contains 50 chapters (22 new) while the Drug Product volume contains 26 chapters (20 new). Drug Product focuses on the development, chemical engineering and unit operations specific to the design, formulation, and manufacture of drug products. Drug product unit operations include wet and dry granulations, tableting, spray-coating, spray drying, lyophilization, hot-melt extrusion, controlled release, and direct compression for continuous processing. Technology transfer and scale-up of batch processes are exemplified experimentally and computationally. For the current professionals, in-silico process modeling tools that streamline experimental screening approaches is presented. The emerging field of continuous drug product manufacturing is also discussed. Although continuous manufacturing is in the mainstream for chemical engineers, it is unique in the pharmaceutical industry with regard to the range of scales and the complex economics associated with transforming existing batch-plant capacity to continuous processing. Basic analytics for quantitation of drug product quality attributes, such as potency, purity, content uniformity, and dissolution, are addressed with consideration of the applied statistics, process analytical technology (PAT), and process control. In addition we introduce contemporary methods of data analysis and extend these concepts into Quality by Design strategies for regulatory filings. Finally, technical chapters on commonly used software tools with examples are an important part of this book.
内容简介:
目次:
全文链接:
http://www.itextbook.cn/f/book/bookDetail?bookId=dd357e664aa84051b88b266245b12aa2
读者对象:
实体信息
页码:
其它信息
原版ISBN:
书评:
扩展信息
相关附件