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关键词:
Neural Stem Cells in Health and Disease
书目信息
ISBN:
9789814623186
本馆索书号:
中图分类号:
Q42
中文译名:
健康与疾病中的神经干细胞
作者:
Ashok K Shetty
编者:
语种:
英语
出版信息
出版社:
WSPC
出版地:
出版年:
2015
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原版
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内容简介:
This book is a comprehensive guide on neural stem cell behavior in health and disease. The book confers the altered behavior of endogenous neural stem cells in neurodegenerative disease conditions and the prospects of neural stem cell therapy for alleviating brain dysfunction in a variety of neurodegenerative disorders.Neural stem cell activity and neurogenesis in the adult brain is now confirmed in virtually all mammalian species including humans. Hence, a series of chapters in the first half of the book discusses the current knowledge on mechanisms of neural stem cell activity, the extent and functional significance of neurogenesis in the adult brain under normal, aged and disease environments, the susceptibility of neural stem cells and the plasticity of neurogenesis to alcohol, drugs of abuse and anesthetic agents, and advanced techniques that trigger neurogenesis in non-neurogenic regions.A second series of chapters in this book are focused on discussing the promise and efficacy of grafting of neural stem cells and/or other stem cells for treating neurological disorders such as Parkinson's disease, stroke, temporal lobe epilepsy, Alzheimer's disease and spinal cord injury. The final chapter confers on advances that are made in manufacturing a variety of neural cell types from human pluripotent stem cells that can be used as donor cells for cell transplantation.
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